Additional biomarkers and emm types associated with group A streptococcal toxic shock syndrome: a Japanese nationwide observational study
WBC < 4,000/µL and CK level ≥ 300 U/L on admission are additional relevant biomarkers for STSS prediction. The most predominant iGAS type, emm1, was significantly associated with STSS.
Authors
- Kimiko Ubukata (ORCID: https://orcid.org/0000-0001-8934-2477)
- Misako Takata
- Miyuki Morozumi
- Yukio Sato (ORCID: https://orcid.org/0000-0001-5981-7224)
- Shigeo Hanada (ORCID: https://orcid.org/0000-0002-8435-4425)
- Satoshi Iwata (ORCID: https://orcid.org/0000-0002-9160-4461)
- Takeaki Wajima (ORCID: https://orcid.org/0000-0001-9506-707X)
- Junichi Sasaki (ORCID: https://orcid.org/0000-0002-5190-8524)
Institutions
- Tokyo Medical University (JP)
- Keio University (JP)
- Meijo University (JP)
Publication Details
- Journal
- European Journal of Clinical Microbiology & Infectious Diseases
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1007/s10096-025-05116-6
- Citations
- 4
- Primary Topic
- Streptococcal Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.51
Funders
- Ministry of Health, Labour and Welfare