COPB2 promotes hepatocellular carcinoma progression through regulation of YAP1 nuclear translocation
Our findings suggest that COPB2/YAP1 affects the drug sensitivity of HCC cells to DDP and that targeting COPB2/YAP1 may be a promising strategy for the precision treatment of HCC.
Authors
- Suqing Zhang (ORCID: https://orcid.org/0000-0001-8475-4747)
- Xianlin Guo
- Biao Wu (ORCID: https://orcid.org/0000-0003-0182-9454)
- Liang Chen (ORCID: https://orcid.org/0000-0001-7371-3130)
- Zhishi Wu
Institutions
- Second Military Medical University (CN)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Nantong Tumor Hospital (CN)
- Zhengzhou People's Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.058085
- Citations
- 3
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 3.45