The contribution of cardiopulmonary exercise testing in the familial screening for dilated and non-dilated left ventricular cardiomyopathies: case series
Family screening in relatives of DCM and NDLVC patients, particularly in genotype-positive/phenotype-negative subjects, remains challenging due to difficulties in assessing the subtle abnormalities that may represent an initial clinical manifestation of the disease and support early treatment initiation. A more accurate and comprehensive familial screening may be achieved by integrating ECG and echocardiogram-the current first-line assessments-with data from additional tools, such as global longitudinal strain on echocardiogram, cardiac magnetic resonance, Holter ECG, and CPET.
Authors
- Teresa Maria Capovilla (ORCID: https://orcid.org/0000-0002-9153-4686)
- Gianfranco Sinagra (ORCID: https://orcid.org/0000-0003-2700-8478)
- Martina Setti (ORCID: https://orcid.org/0000-0002-3618-2833)
- Marco Merlo (ORCID: https://orcid.org/0000-0002-1022-3131)
- Matteo Dal Ferro (ORCID: https://orcid.org/0000-0002-2310-0448)
- Eva Del Mestre (ORCID: https://orcid.org/0009-0001-5432-9288)
- Marco Cittar (ORCID: https://orcid.org/0000-0003-0577-6281)
- Alessia Paldino (ORCID: https://orcid.org/0000-0002-5823-3777)
Institutions
- University of Verona (IT)
- University of Trieste (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- ERN GUARD-Heart (NL)
- Azienda Sanitaria Universitaria Integrata di Trieste (IT)
- Misericordia University (US)
Publication Details
- Journal
- European Heart Journal - Case Reports
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1093/ehjcr/ytaf162
- Primary Topic
- Cardiovascular Effects of Exercise
- Type
- article
- Field-Weighted Citation Impact
- 0.00