Iron deficiency in pregnancy and its association with blood lead and manganese levels in offspring in Benin, Sub-Saharan Africa

Elevated BLL and BML in infants were positively associated with ID and/or IDA prenatally during at least one ANC visit, while in infancy, infant ID and IDA were positively associated with elevated BLL only. Infants with ID and IDA showed higher BLL but not BML. This suggests that ID prenatally and during infancy may contribute to high blood lead concentrations in infants, which can lead to neurotoxicity. Treating ID and IDA is critical to prevent toxicity caused by high BLL in infants.

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Publication Details

Journal
Early Human Development
Published
2025-04-08
DOI
https://doi.org/10.1016/j.earlhumdev.2025.106255
Primary Topic
Child Nutrition and Water Access
Type
article
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article

Iron deficiency in pregnancy and its association with blood lead and manganese levels in offspring in Benin, Sub-Saharan Africa

Shukrullah Ahmadi, Pierre Dumas, Florence Bodeau‐Livinec, Pierre Ayotte et al.
Early Human Development
Child Nutrition and Water Access
article

Iron deficiency in pregnancy and its association with blood lead and manganese levels in offspring in Benin, Sub-Saharan Africa

Shukrullah Ahmadi, Pierre Dumas, Florence Bodeau‐Livinec, Pierre Ayotte, Philippe Glorennec, Roméo Zoumenou, Achille Massougbodji, Barbara Le Bot, Raymond Van Huizen
article en

Abstract

Elevated BLL and BML in infants were positively associated with ID and/or IDA prenatally during at least one ANC visit, while in infancy, infant ID and IDA were positively associated with elevated BLL only. Infants with ID and IDA showed higher BLL but not BML. This suggests that ID prenatally and during infancy may contribute to high blood lead concentrations in infants, which can lead to neurotoxicity. Treating ID and IDA is critical to prevent toxicity caused by high BLL in infants.

Early Human DevelopmentVol. 205
Inserm (FR), Mère et enfant en milieu tropical : pathogènes, système de santé et transition épidémiologique (FR), Institut National de Santé Publique du Québec (CA), The Quebec Population Health Research Network (CA), Institut de Recherche en Santé, Environnement et Travail (FR), Université de Rennes (FR)
Zero hunger
Openalex Percentile: Top 92%
Child Nutrition and Water Access
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Iron deficiency in pregnancy and its association with blood lead and manganese levels in offspring in Benin, Sub-Saharan Africa — Shukrullah Ahmadi, Pierre Dumas, et al. · Early Human Development (2025) | TGRS Research Map | TGRS