In vivo effects of bempedoic acid on microdosed CYP probe drugs

In healthy volunteers, BA was a mild inducer of CYP2C19 and did not affect CYP3A or CYP2D6 activity.

Authors

Jürgen Burhenne (ORCID: https://orcid.org/0000-0002-2190-1698)
Antje Blank (ORCID: https://orcid.org/0000-0001-8743-5194)
Felicitas Stoll (ORCID: https://orcid.org/0000-0003-3005-0546)
Salvatore Amato

Institutions

Heidelberg University (DE)
University Hospital Heidelberg (DE)

Publication Details

Journal: Frontiers in Pharmacology
Published: 2025-04-08
DOI: https://doi.org/10.3389/fphar.2025.1544956
Citations: 2
Primary Topic: Pharmacogenetics and Drug Metabolism
Type: article
Field-Weighted Citation Impact: 3.11

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article

In vivo effects of bempedoic acid on microdosed CYP probe drugs

Jürgen Burhenne, Antje Blank, Felicitas Stoll, Salvatore Amato

Apr 8, 2025

2 citations

Frontiers in Pharmacology

Pharmacogenetics and Drug Metabolism

3.11

article

In vivo effects of bempedoic acid on microdosed CYP probe drugs

Jürgen Burhenne, Antje Blank, Felicitas Stoll, Salvatore Amato

April 8, 2025article en

2 citations

Abstract

In healthy volunteers, BA was a mild inducer of CYP2C19 and did not affect CYP3A or CYP2D6 activity.

Frontiers in PharmacologyVol. 16

Heidelberg University (DE), University Hospital Heidelberg (DE)

Openalex Percentile: Top 11%

Pharmacogenetics and Drug Metabolism

3.11

DOI Open Access PDF OpenAlex

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In vivo effects of bempedoic acid on microdosed CYP probe drugs — Jürgen Burhenne, Antje Blank, et al. · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS