Investigation of anti-quorum sensing inhibition activity of some boron compounds

Boron is one of the important elements for organisms, especially for plants and animals. The importance of boron for humanity is increasing, and its uses are parallelly expanding. In this study, the quorum-sensing inhibition effects of five different boron compounds were investigated. The quorum-sensing inhibition assay was performed on CV026 and CV12472 using the broth dilution method. Considering the results of this study, it was determined that the highest violacein inhibition activity was provided by sodium tetraborate with 74.46%. Based on the quorum sensing activity, it was revealed that the minimum inhibitory concentration (MIC) value of boron oxide and sodium tetraborate provided the highest inhibition rate 95.15%. When the anti-quorum sensing activity data obtained from the study are examined, it was seen that these boron compounds showed high activity and should be supported by different tests such as animal experiments.