Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke

ABCA1, CLEC4E, and IRS2 were identified as potential key biomarkers and therapeutic targets for CS and IS. Autophagy and neutrophil infiltration may represent the common mechanisms linking these two diseases.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-04-08
DOI
https://doi.org/10.3389/fneur.2025.1567902
Primary Topic
Cerebrovascular and genetic disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke

Xuan Wang, Xueyuan Liu
Frontiers in Neurology
Cerebrovascular and genetic disorders
article

Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke

Xuan Wang, Xueyuan Liu
article en

Abstract

ABCA1, CLEC4E, and IRS2 were identified as potential key biomarkers and therapeutic targets for CS and IS. Autophagy and neutrophil infiltration may represent the common mechanisms linking these two diseases.

Frontiers in NeurologyVol. 16
Tongji University (CN), Shanghai Jiao Tong University (CN), Tongren Hospital (CN), Shanghai Tenth People's Hospital (CN)
Openalex Percentile: Top 88%
Cerebrovascular and genetic disorders
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Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke — Xuan Wang, Xueyuan Liu · Frontiers in Neurology (2025) | TGRS Research Map | TGRS