A retrospective analysis comparing metagenomic next-generation sequencing with conventional microbiology testing for the identification of pathogens in patients with severe infections
Our data indicated that mNGS had significant auxiliary value in the clinical diagnosis and treatment for critically ill patients, especially for those with negative CMT results and clinically undefined infections. mNGS could broaden the detection scope, especially for special pathogens, and improve the detection rate, providing powerful assistance for early clinical diagnosis and treatment.
Authors
- Xiaohang Hu (ORCID: https://orcid.org/0009-0003-0337-4841)
- Mingrui Chen (ORCID: https://orcid.org/0009-0007-2702-2567)
- Yu Qiao (ORCID: https://orcid.org/0000-0001-6749-0575)
- Yuanyuan Qiao (ORCID: https://orcid.org/0000-0002-3573-9847)
- Xiaowei Liu (ORCID: https://orcid.org/0000-0001-7585-5159)
- Min Kong
- Fei Hou (ORCID: https://orcid.org/0000-0002-3512-5589)
- Ya Shi
- Liqing Jiang (ORCID: https://orcid.org/0000-0003-1828-1368)
Institutions
- Affiliated Hospital of Jining Medical University (CN)
- Jining Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.3389/fcimb.2025.1530486
- Citations
- 4
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 5.27