Risk factors and mortality in children with severe pertussis: the role of exchange transfusion in a PICU
High WBC counts are significantly correlated with increased mortality risk in severe pertussis children, with a threshold of 48.58 × 10^9/L marking high risk. Although exchange transfusion can reduce WBC counts and improve symptoms, its benefit is limited in patients with severe secondary infections, necessitating tailored treatment strategies.
Authors
- Chenjun Liu (ORCID: https://orcid.org/0000-0002-4118-3320)
- Yanran Qin
- Song Chen (ORCID: https://orcid.org/0000-0001-6412-5740)
- Feng Xu (ORCID: https://orcid.org/0000-0002-3095-2147)
- Junming Huo
Institutions
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- The Italian Journal of Pediatrics/Italian journal of pediatrics
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1186/s13052-025-01951-7
- Citations
- 9
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 10.65