Abnormally high expression of CHI3L1 in peripheral blood mononuclear cells and serum and their potential diagnosis and prediction from lymphoma patients
This study demonstrates that elevated CHI3L1 expression is strongly associated with lymphoma onset, progression, severity, and poor prognosis, underscoring its potential as both a diagnostic and prognostic biomarker. Moreover, CHI3L1 may contribute to lymphoma progression by regulating key biological processes.
Authors
- Yanqun Huang (ORCID: https://orcid.org/0000-0002-4427-2767)
- Houzhuo Luo (ORCID: https://orcid.org/0009-0009-2374-8314)
- Yuxing He (ORCID: https://orcid.org/0000-0001-5628-8080)
- Rong Liu (ORCID: https://orcid.org/0009-0002-9546-0482)
- Chao Wang (ORCID: https://orcid.org/0009-0001-3192-253X)
- Ming Lei (ORCID: https://orcid.org/0000-0001-7971-6447)
- Juan Liang
- Langui Tang
- Yan Gao (ORCID: https://orcid.org/0009-0007-2701-2115)
- Kaiyun Guo
Institutions
- Central South University (CN)
- Soochow University (CN)
- The First People's Hospital of Changde (CN)
- Fourth People's Hospital of Changzhou (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.3389/fimmu.2025.1557802
- Citations
- 1
- Primary Topic
- Studies on Chitinases and Chitosanases
- Type
- article
- Field-Weighted Citation Impact
- 0.81