Prevalence of cerebral amyloid angiopathy and its correlation with Alzheimer's disease and cognition in an autopsy‐confirmed cohort from China
First reporting of cerebral amyloid angiopathy (CAA) based on an autopsy-confirmed cohort from China.The prevalence of CAA was high in the elderly Chinese sample.Age and apolipoprotein E (<i>APOE</i>) ε4 allele were related to the prevalence of CAA.CAA and Alzheimer's disease (AD) were frequently co-occurred and significantly associated.Subjects with both CAA and AD exhibited aggravated cognitive impairment.
Authors
- Chao Ma (ORCID: https://orcid.org/0000-0003-1346-6961)
- Zhen Chen (ORCID: https://orcid.org/0000-0002-3096-8501)
- Xiang‐Sha Yin (ORCID: https://orcid.org/0009-0006-8330-1133)
- Wenying Qiu (ORCID: https://orcid.org/0000-0003-4906-8746)
- Di Zhang (ORCID: https://orcid.org/0000-0002-5028-051X)
- Xue Wang (ORCID: https://orcid.org/0000-0003-1964-4124)
- Wei Wu (ORCID: https://orcid.org/0000-0002-1269-9045)
- Jun Ni (ORCID: https://orcid.org/0000-0002-5939-8856)
- Yongmei Chen (ORCID: https://orcid.org/0000-0003-1461-4890)
- Yuanyuan Xu (ORCID: https://orcid.org/0000-0002-2420-9058)
- Xiaojing Qian
- Jianru Sun
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Chinese Institute for Brain Research (CN)
Publication Details
- Journal
- Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/dad2.70100
- Citations
- 3
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 4.17