First-in-Human Trial of NRTX-1001 GABAergic Interneuron Cell Therapy for Focal Epilepsy - Updated Clinical Trial Results (P8-9.003)
To present updated findings from a first-in-human, open-label study of NRTX-1001, an allogeneic GABAergic interneuron therapy, for unilateral drug-resistant temporal lobe epilepsy with mesial temporal sclerosis (NCT05135091).
Authors
- Kim J. Burchiel (ORCID: https://orcid.org/0000-0002-6238-9424)
- Rose Larios
- David Spencer (ORCID: https://orcid.org/0000-0001-9751-235X)
- Yves Maury
- Alessandro Bulfone
- Jihye Jung (ORCID: https://orcid.org/0000-0001-9186-7176)
- Cory R. Nicholas
- Seonok Lee
- Marina Bershteyn
- Jerry J. Shih (ORCID: https://orcid.org/0000-0002-0680-0362)
- Harish Babu (ORCID: https://orcid.org/0000-0002-9837-6318)
- Luis C. Fuentealba
- John Hixson (ORCID: https://orcid.org/0000-0003-3053-6474)
- Catherine Priest
- Sepehr Sani (ORCID: https://orcid.org/0000-0002-1737-5269)
- Sonja Kriks
- Tia J. Kowal (ORCID: https://orcid.org/0000-0003-3879-4718)
- Derek G. Southwell (ORCID: https://orcid.org/0000-0001-6465-3869)
- Matthew W. Luedke (ORCID: https://orcid.org/0000-0002-1564-0241)
- David Blum (ORCID: https://orcid.org/0000-0003-2473-7069)
- Rebecca O’Dwyer (ORCID: https://orcid.org/0000-0003-2461-8457)
- Sharona Ben‐Haim (ORCID: https://orcid.org/0000-0002-3864-6443)
- Brianna G Feld
- Gautam Banik
- Holly Finefrock
- Manher Joshi
- Sergei Shevchuk
- Robert L. Beach
- S. Madrid
Institutions
- Rush University Medical Center (US)
- Duke University (US)
- UC San Diego Health System (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000210525
- Citations
- 4
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.56