Time to Prerandomization Seizure Count Design Sufficiently Assessed the Safety and Tolerability of Perampanel for the Treatment of Focal Seizures (P8-9.004)
We evaluated if the Time to Pre-randomization monthly Seizure Count (T-PSC) design could replicate tolerability and safety conclusions of three placebo-controlled trials of perampanel for focal-onset seizures.
Authors
- Wesley T. Kerr (ORCID: https://orcid.org/0000-0002-5546-5951)
- Anna Patten (ORCID: https://orcid.org/0000-0003-0036-9732)
- Jocelyn Cheng
- Jacqueline A. French (ORCID: https://orcid.org/0000-0003-2242-8027)
- Leock Y. Ngo (ORCID: https://orcid.org/0000-0002-8184-1367)
- Liang Zhu
- Lavanya Biju
Institutions
- University of Pittsburgh (US)
- Neurelis (United States) (US)
- Comprehensive Clinical Research (US)
- Eisai (Japan) (JP)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211954
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00