Intracerebroventricular Injection of Autologous Adipose-Derived Stem Cells for the Treatment of Alzheimer’s Disease: Experience with the First of Three, 3-patient Cohorts in a “First-in-Human” Phase 1 FDA Trial (P12-3.005)
We are testing the safety of using autologous, abdominal fat-derived, Wnt-activated stem cells injected into the ventricles of the brain. Secondary endpoints are reviewed.
Authors
- Christopher Duma (ORCID: https://orcid.org/0000-0003-3943-2030)
- Jessica L. Buxton
- Hans S. Keirstead (ORCID: https://orcid.org/0000-0002-7086-4408)
- Karlyssa Chung
- Sawyer H. Farmer (ORCID: https://orcid.org/0009-0006-4160-9535)
- Robert Lynn
- Gabriel Nistor
- Zoe Hareng
Institutions
- Tissue Regeneration Systems (United States) (US)
- RTI Surgical (United States) (US)
- Regenerative Medicine Institute (MX)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000210642
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00