Body Fat Distribution and Glucose Homeostasis Is Affected by Perinatal Exposure to High Dietary Advanced Glycation End Products (AGEs) in Male Offspring
These results indicate that perinatal exposure to a maternal diet elevated in AGEs causes deficits in perinatal growth and impairment in glucose hemostasis in male mice. These findings suggest that AGEs may represent an important new class of mediators of adiposity and the metabolic syndrome.
Authors
- Maureen Charron (ORCID: https://orcid.org/0000-0001-6353-5692)
- Zaher Merhi (ORCID: https://orcid.org/0000-0002-7952-1428)
- Xiu Quan Du
Institutions
- Albert Einstein College of Medicine (US)
- Maimonides Medical Center (US)
- New Hope Fertility Center (US)
Publication Details
- Journal
- American Journal of Reproductive Immunology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/aji.70073
- Citations
- 1
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- American Society for Reproductive Medicine
- Albert Einstein College of Medicine, Yeshiva University