Multimodal Investigation of Brain Structural Changes, Neurocognitive Function, and Sleep Disruptions in Myotonic Dystrophy Type 1 (P5-2.008)

The primary objective of this study is to investigate the alterations in brain white matter integrity, neurocognitive functioning, and sleep architecture in individuals living with Myotonic Dystrophy Type 1 (DM1). This study aims to identify neuroimaging biomarkers and patterns in polysomnography (PSG) that are associated with cognitive impairment, structural brain changes, and disrupted sleep.