Unmasking Lamotrigine Toxicity: Two Cases with Ocular Red Herrings and the Crucial Role of Vigilant Pharmacological Assessment (P9-11.001)

Lamotrigine (LTG) is a commonly used anticonvulsant and mood stabilizer. While generally well-tolerated, lamotrigine toxicity can occur. Presentation of lamotrigine toxicity can be diverse and include seizure, ocular abnormalities, ataxia, and encephalopathy, mimicking other neurological conditions, causing diagnostic challenges. Ocular findings are varied and can include diplopia, downbeat nystagmus, and gaze palsy.