Phase 1 Clinical Data with Orexin Receptor 2 (OX2R) Agonist, ORX750, in Acutely Sleep-Deprived Healthy Participants (P1-4.003)

To evaluate safety and wake-promoting effects of single and multiple oral doses of ORX750 in a first-in-human clinical study.

Authors

Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000209036
Citations
1
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
2.12
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article

Phase 1 Clinical Data with Orexin Receptor 2 (OX2R) Agonist, ORX750, in Acutely Sleep-Deprived Healthy Participants (P1-4.003)

Emiliangelo Ratti, Saurabh Saha, Jennifer Y. Kong, Deborah Hartman et al.
1 citations
Neurology
Sleep and related disorders
2.12
article

Phase 1 Clinical Data with Orexin Receptor 2 (OX2R) Agonist, ORX750, in Acutely Sleep-Deprived Healthy Participants (P1-4.003)

Emiliangelo Ratti, Saurabh Saha, Jennifer Y. Kong, Deborah Hartman, Mario Accardi, Ellie Im
article en
1 citations

Abstract

To evaluate safety and wake-promoting effects of single and multiple oral doses of ORX750 in a first-in-human clinical study.

NeurologyVol. 104(7_Supplement_1)
Openalex Percentile: Top 15%
Sleep and related disorders
2.12
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Phase 1 Clinical Data with Orexin Receptor 2 (OX2R) Agonist, ORX750, in Acutely Sleep-Deprived Healthy Participants (P1-4.003) — Emiliangelo Ratti, Saurabh Saha, et al. · Neurology (2025) | TGRS Research Map | TGRS