Molecular Testing Using <scp>ThyGeNEXT</scp>/<scp>ThyraMIR</scp> in Thyroid Nodules With Indeterminate Cytology: A Single Medical Institute Experience

This study showed that more than half (56%) of the thyroid nodules with indeterminate cytology had benign molecular results by MPTX testing. The MPTX test showed moderate to high NPV and moderate PPV, suggesting that the MPTX test can be useful as an ancillary study to further risk-stratify cytologically indeterminate thyroid nodules. It is critical, however, to know the limitations of this assay, and the molecular results should be considered in correlation with clinical and radiologic findings.