Higher blood–brain barrier leakage in schizophrenia-spectrum disorders: A comparative dynamic contrast-enhanced magnetic resonance imaging study with healthy controls
This is the first study to date reporting BBB leakage in SSDs compared to HCs in multiple brain regions implicated in the disorder. These findings provide insights into disease mechanisms, highlighting the need for further investigation into the role of the BBB in SSDs.
Authors
- Amir Dehsarvi (ORCID: https://orcid.org/0000-0001-7116-9741)
- Boris Papazov (ORCID: https://orcid.org/0000-0002-5274-9166)
- Sophia Stoecklein (ORCID: https://orcid.org/0000-0003-0325-4674)
- Isabel Maurus (ORCID: https://orcid.org/0000-0002-6208-5180)
- Klaus Seelos
- Boris‐Stephan Rauchmann (ORCID: https://orcid.org/0000-0003-4547-6240)
- Daniel Keeser (ORCID: https://orcid.org/0000-0002-0244-1024)
- Matthias Brendel (ORCID: https://orcid.org/0000-0002-9247-2843)
- Florian J. Raabe (ORCID: https://orcid.org/0000-0001-8538-0783)
- Mattia Campana (ORCID: https://orcid.org/0000-0003-4596-4287)
- Vladislav Yakimov (ORCID: https://orcid.org/0000-0001-9559-7492)
- Joanna Moussiopoulou (ORCID: https://orcid.org/0000-0002-0157-6197)
- Julian Melcher
- Nicolai Franzmeier (ORCID: https://orcid.org/0000-0001-9736-2283)
- Elias M. Wagner (ORCID: https://orcid.org/0000-0002-7147-6167)
- Emanuel Boudriot (ORCID: https://orcid.org/0000-0001-6083-6318)
- Iris Jäger
- Lisa Löhrs (ORCID: https://orcid.org/0000-0001-6578-3649)
- Marcel S. Kallweit
- Alkomiet Hasan (ORCID: https://orcid.org/0000-0002-2662-9742)
- CDP Working Group
- Isabel Lutz
- Hannah Toth
- Peter Falkai
Institutions
- University of Augsburg (DE)
- University Hospital Augsburg (DE)
- LMU Klinikum (DE)
- Munich Cluster for Systems Neurology (DE)
- Max Planck Institute of Psychiatry (DE)
- Bezirkskrankenhaus Augsburg (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Brain Behavior and Immunity
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1016/j.bbi.2025.04.003
- Citations
- 14
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 19.04
Funders
- Deutsche Forschungsgemeinschaft
- Ludwig-Maximilians-Universität München