Comparison of tendon healing using local platelet-rich plasma, erythropoietin, and erythropoietin-bevacizumab in a rat achilles tenotomy model
Our study results showed that EPO-BEVA enhanced tendon healing via vascular and matrix modulation, although the lack of a BEVA-only group limits conclusions on synergy. Future studies with larger sample sizes, including BEVA monotherapy, optimized dosing strategies, and long-term evaluations are needed to better clarify these effects and refine treatment strategies in regenerative medicine.
Authors
- Özgür Bulmuş (ORCID: https://orcid.org/0000-0001-7736-402X)
- Gülay Turan (ORCID: https://orcid.org/0000-0002-3702-8811)
- Emrah Özcan (ORCID: https://orcid.org/0000-0002-6373-4744)
- Ahmet Emrah Açan (ORCID: https://orcid.org/0000-0001-7116-8773)
- R. Buğra Hüsemoğlu (ORCID: https://orcid.org/0000-0003-1979-160X)
- Aslı Karakılıç (ORCID: https://orcid.org/0000-0001-7788-4949)
- Memduh Aydın (ORCID: https://orcid.org/0009-0006-6124-7842)
- Özge Özmen
Institutions
- Erzincan Binali Yıldırım University (TR)
Publication Details
- Journal
- Joint Diseases and Related Surgery
- Published
- 2025-04-01
- DOI
- https://doi.org/10.52312/jdrs.2025.2234
- Citations
- 1
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.72