A Devastating Detour: When Immune Checkpoint Inhibitors Triggers CNS Vasculitis (P11-14.006)

Immune Checkpoint inhibitors (ICI) are increasingly used to treat solid organ tumors, but they can cause a variety of immune-related adverse events (irAEs). Neurologic irAEs are reported in about 1–12% of patients, with central nervous system (CNS) vasculitis being rare. Here, we present a case of ICI-related CNS vasculitis to increase awareness of this devastating complication.

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000210858
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A Devastating Detour: When Immune Checkpoint Inhibitors Triggers CNS Vasculitis (P11-14.006)

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article

A Devastating Detour: When Immune Checkpoint Inhibitors Triggers CNS Vasculitis (P11-14.006)

Praveen Hariharan, Keegan S. Cooke, Abhigyan Datta, A. Parameswaran, Teoh Deanna
article en

Abstract

Immune Checkpoint inhibitors (ICI) are increasingly used to treat solid organ tumors, but they can cause a variety of immune-related adverse events (irAEs). Neurologic irAEs are reported in about 1–12% of patients, with central nervous system (CNS) vasculitis being rare. Here, we present a case of ICI-related CNS vasculitis to increase awareness of this devastating complication.

NeurologyVol. 104(7_Supplement_1)
University of Minnesota (US), University of Minnesota System (US)
Openalex Percentile: Top 89%
Brain Metastases and Treatment
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