Phase 3 Trial Designs Evaluating Riliprubart, a C1s-Complement Inhibitor, in Chronic Inflammatory Demyelinating Polyneuropathy (P10-11.027)

To present two Phase 3 trial designs which will evaluate riliprubart in 1) people with chronic inflammatory demyelinating polyneuropathy (CIDP) who experienced an inadequate response or failure to at least one line of treatment (Standard-of-care [SOC]-refractory) and 2) responders to IVIg with residual disability despite maintenance SOC treatment.

Authors

Institutions

Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000208529
Citations
2
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
2.78
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Phase 3 Trial Designs Evaluating Riliprubart, a C1s-Complement Inhibitor, in Chronic Inflammatory Demyelinating Polyneuropathy (P10-11.027)

Richard A. Lewis, Claudia Sommer, Luís Querol, Miguel Alonso‐Alonso et al.
2 citations
Neurology
Peripheral Neuropathies and Disorders
2.78
article

Phase 3 Trial Designs Evaluating Riliprubart, a C1s-Complement Inhibitor, in Chronic Inflammatory Demyelinating Polyneuropathy (P10-11.027)

Richard A. Lewis, Claudia Sommer, Luís Querol, Miguel Alonso‐Alonso, Erik Wallstroem, Pieter A. van Doorn, Nazem Atassi, Jeffrey A. Allen, Xiaodong Luo, Ingemar S.J. Merkies
article en
2 citations

Abstract

To present two Phase 3 trial designs which will evaluate riliprubart in 1) people with chronic inflammatory demyelinating polyneuropathy (CIDP) who experienced an inadequate response or failure to at least one line of treatment (Standard-of-care [SOC]-refractory) and 2) responders to IVIg with residual disability despite maintenance SOC treatment.

NeurologyVol. 104(7_Supplement_1)
Cedars-Sinai Medical Center (US), University of Minnesota (US), Hospital de Sant Pau (ES), Erasmus MC (NL), Maastricht University (NL), AVEO Oncology (United States) (US), Centre for Biomedical Network Research on Rare Diseases (ES), Sanofi (United States) (US), Centro de Investigación Biomédica en Red (ES), University of Curaçao (CW), Universitätsklinikum Würzburg (DE), Klinik und Poliklinik für Neurologie (DE)
Good health and well-being
Openalex Percentile: Top 11%
Peripheral Neuropathies and Disorders
2.78
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.