Methylglyoxal-Induced Glycation of Plasma Albumin: From Biomarker Discovery to Clinical Use for Prediction of New-Onset Diabetes in Individuals with Prediabetes

MGH-ALB219-225 is a novel and stable peptide biomarker of MGO-glycated ALB, whose plasma levels are positively associated with an increased risk of NOD in individuals with prediabetes, independently of traditional risk factors. ClinicalTrials.gov Registration Number: NCT01218061.

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Publication Details

Journal
Clinical Chemistry
Published
2025-04-07
DOI
https://doi.org/10.1093/clinchem/hvaf035
Citations
4
Primary Topic
Advanced Glycation End Products research
Type
article
Field-Weighted Citation Impact
5.27

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article

Methylglyoxal-Induced Glycation of Plasma Albumin: From Biomarker Discovery to Clinical Use for Prediction of New-Onset Diabetes in Individuals with Prediabetes

Chloé Chevalier, Bertrand Cariou, Cédric Caradeuc, Arsênio Rodrigues Oliveira et al.
4 citations
Clinical Chemistry
Advanced Glycation End Products research
5.27
article

Methylglyoxal-Induced Glycation of Plasma Albumin: From Biomarker Discovery to Clinical Use for Prediction of New-Onset Diabetes in Individuals with Prediabetes

Chloé Chevalier, Bertrand Cariou, Cédric Caradeuc, Arsênio Rodrigues Oliveira, Chloé Cloteau, Georges Nouadje, Gildas Bertho, Nicolas Giraud, Samy Hadjadj, Victoria Pakulska, Maxime Carpentier, Edith Bigot‐Corbel, Mikaël Croyal, Cédric Le May, Yohann Couté, Marine P. M. Letertre, Matthieu Wargny
article en
4 citations

Abstract

MGH-ALB219-225 is a novel and stable peptide biomarker of MGO-glycated ALB, whose plasma levels are positively associated with an increased risk of NOD in individuals with prediabetes, independently of traditional risk factors. ClinicalTrials.gov Registration Number: NCT01218061.

Clinical ChemistryVol. 71(6)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris Cité (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Cambia (AU), Centre Hospitalier Universitaire de Nantes (FR), CEA Grenoble (FR), Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (FR), Sebia (France) (FR), Chimie et Interdisciplinarité, Synthèse, Analyse, Modélisation (FR), Institut du Thorax (FR), Hôpital Laennec (FR), GenProMarkers (United States) (US), Université Grenoble Alpes (FR), Nantes Université (FR)
Agence Nationale de la Recherche, Direction Générale de l’offre de Soins
Industry, innovation and infrastructure
Openalex Percentile: Top 5%
Advanced Glycation End Products research
5.27
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