Sitagliptin regulates the AMPK/NF-κB signaling pathway to alleviate lipopolysaccharide-induced inflammatory responses and promote osteogenic differentiation in rat bone marrow mesenchymal stem cells
Sitagliptin suppresses rat BMSCs inflammation while promoting osteogenesis through the modulation of AMPK/NF-κB signaling activity, thereby mitigating the functional impairment of rat BMSCs under inflammatory microenvironmental conditions.
Authors
- Pei Wang (ORCID: https://orcid.org/0000-0002-1650-3353)
- Min Liu (ORCID: https://orcid.org/0000-0001-7076-5066)
- Xi Yao (ORCID: https://orcid.org/0000-0002-9276-4686)
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- Archives of Oral Biology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.archoralbio.2025.106253
- Citations
- 2
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Luzhou Science and Technology Bureau