Intraductal papillary neoplasm of the bile duct in the middle east: Case report

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare premalignant tumor characterized by papillary growth within the bile ducts, predominantly reported in East Asia. We present a 64-year-old male diagnosed with IPNB with focal stromal invasion, managed successfully with surgical resection. The case highlights unique endoscopic, imaging, and histopathological findings, and provides valuable data describing the unusual presentation of the case and the challenges faced in making the diagnosis. To our knowledge, this is the first reported case from the Middle East, emphasizing the rarity of IPNB in the region. This report underscores the importance of early diagnosis, proper imaging, and clear resection margins for optimal outcomes.

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Publication Details

Journal
Surgery Case Reports
Published
2025-04-08
DOI
https://doi.org/10.1016/j.sycrs.2025.100099
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
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article

Intraductal papillary neoplasm of the bile duct in the middle east: Case report

Hanood Abu Rass, Khaled Demyati, Ameer Awashra, Fathi Milhem et al.
Surgery Case Reports
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Intraductal papillary neoplasm of the bile duct in the middle east: Case report

Hanood Abu Rass, Khaled Demyati, Ameer Awashra, Fathi Milhem, Amr Khaled, Orabi Hajjeh, Usama Al Khuffash
article en

Abstract

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare premalignant tumor characterized by papillary growth within the bile ducts, predominantly reported in East Asia. We present a 64-year-old male diagnosed with IPNB with focal stromal invasion, managed successfully with surgical resection. The case highlights unique endoscopic, imaging, and histopathological findings, and provides valuable data describing the unusual presentation of the case and the challenges faced in making the diagnosis. To our knowledge, this is the first reported case from the Middle East, emphasizing the rarity of IPNB in the region. This report underscores the importance of early diagnosis, proper imaging, and clear resection margins for optimal outcomes.

Surgery Case ReportsVol. 5
An-Najah National University (PS), National University Hospital (SG)
Zero hunger
Openalex Percentile: Top 88%
Cholangiocarcinoma and Gallbladder Cancer Studies
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