In vivo quantification of collagen-induced arthritis mouse model by three-dimensional volumetric ultrasound and color Doppler
We demonstrated that 3D volumetric ultrasound and color Doppler is a noninvasive, quantitative tool for evaluating CIA mice in vivo. Despite certain limitations, those technology significantly enhance our ability to monitor disease progression and severity, assess therapeutic interventions, and reduce reliance on invasive techniques.
Authors
- Qianqian Liang (ORCID: https://orcid.org/0000-0001-8797-7778)
- Tengteng Wang (ORCID: https://orcid.org/0000-0001-9001-186X)
- Hao Xu (ORCID: https://orcid.org/0000-0003-2598-4010)
- Qingyun Jia
- Lei Wu (ORCID: https://orcid.org/0009-0006-9769-3529)
Institutions
- Linyi People's Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1371/journal.pone.0321124
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province