Prenatal exposure to per-and polyfluoroalkyl substances and its association with Developmental Defects of Enamel (DDE) and dental caries in 4 years old children: Findings from Shanghai birth cohort
Although no overall association was observed between PFAS mixtures and oral health outcomes, certain short-chain PFAS compounds, such as PFBS and PFHpA, demonstrated distinct effects on enamel defects. Further research is warranted to clarify the biological mechanisms underlying these associations and to examine the role of PFAS exposure in other populations.
Authors
- Huning Wang
- KaiweiSa Abuduxukuer
- Dongxin Da
- Chuchu Wang (ORCID: https://orcid.org/0000-0002-1851-5534)
- Ying Zhang (ORCID: https://orcid.org/0000-0003-1197-8445)
- Jun Zhang (ORCID: https://orcid.org/0000-0003-1706-1611)
- Hao Zhang (ORCID: https://orcid.org/0000-0002-0223-0681)
- Xinyi Luo (ORCID: https://orcid.org/0000-0001-5225-1790)
- Jianfeng Luo (ORCID: https://orcid.org/0000-0002-9833-0416)
- Xiaoli Zeng
- Jin Yu
- Wenjian Lu
Institutions
- University of Pittsburgh (US)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- XinHua Hospital (CN)
- Shanghai Stomatological Hospital (CN)
- Shanghai Public Health Clinical Center (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Environment International
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.envint.2025.109411
- Citations
- 2
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 1.72