Prehospital Ketamine Administration in Benzodiazepine Refractory Status Epilepticus: A Case Series Review
Ketamine appears safe and effective for prehospital treatment of BRSE. Monitoring and intervention for respiratory complications appears necessary, but rates of these complications are consistent with expected rates from seizures and appropriate benzodiazepine dosing. These findings support ketamine's use in EMS for BRSE. Larger prospective studies are needed to confirm safety and efficacy.
Authors
- Bridgette Svancarek
- Jordan Anderson
- Jeffrey Siegler (ORCID: https://orcid.org/0000-0001-5936-443X)
- M. Kowalski (ORCID: https://orcid.org/0000-0001-8594-8666)
- Casey Patrick (ORCID: https://orcid.org/0000-0002-3272-7138)
- Michael C. Perlmutter (ORCID: https://orcid.org/0000-0002-9710-1523)
- Joseph D Finney (ORCID: https://orcid.org/0000-0002-5106-6435)
- Jinli Wang (ORCID: https://orcid.org/0000-0003-0757-136X)
Institutions
- St. Louis Children's Hospital (US)
- Baylor College of Medicine (US)
- Washington University in St. Louis (US)
- University of Michigan (US)
- Harris Health System (US)
- Hennepin County Medical Center (US)
- Montgomery County Department of Health and Human Services (US)
Publication Details
- Journal
- Prehospital Emergency Care
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1080/10903127.2025.2486302
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00