Topology-driven negative sampling enhances generalizability in protein–protein interaction prediction

Authors

Juan Carlos Mobarec (ORCID: https://orcid.org/0000-0001-9482-4294)
Piero Ricchiuto (ORCID: https://orcid.org/0000-0002-8525-6624)
Yupu Liang (ORCID: https://orcid.org/0000-0003-4074-463X)
William R. Mowrey (ORCID: https://orcid.org/0000-0001-9531-9409)
Parham Haddadi (ORCID: https://orcid.org/0000-0002-1876-4055)
Babak Ravandi (ORCID: https://orcid.org/0000-0003-0203-5605)
Naomi H. Philip (ORCID: https://orcid.org/0000-0002-1475-8635)
Tina Eliassi‐Rad (ORCID: https://orcid.org/0000-0002-1892-1188)
Mario Abdelmessih (ORCID: https://orcid.org/0000-0003-2887-5741)
Aparajita Chatterjee (ORCID: https://orcid.org/0000-0002-8662-4863)
Wei Ding (ORCID: https://orcid.org/0009-0008-2629-2167)

Institutions

AstraZeneca (United Kingdom) (GB)
Northeastern University (US)
Santa Fe Institute (US)
Alliance Bioversity International - CIAT (IT)
AstraZeneca (Brazil) (BR)
AstraZeneca (United States) (US)
Alexion Pharma (Switzerland) (CH)

Publication Details

Journal: Bioinformatics
Published: 2025-04-07
DOI: https://doi.org/10.1093/bioinformatics/btaf148
Citations: 2
Primary Topic: Bioinformatics and Genomic Networks
Type: article
Field-Weighted Citation Impact: 1.61

Funders

AstraZeneca
Alexion Pharmaceuticals
Northwestern University

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Topology-driven negative sampling enhances generalizability in protein–protein interaction prediction

Juan Carlos Mobarec, Piero Ricchiuto, Yupu Liang, William R. Mowrey et al.

Apr 7, 2025

2 citations

Bioinformatics

Bioinformatics and Genomic Networks

1.61

article

Topology-driven negative sampling enhances generalizability in protein–protein interaction prediction

Juan Carlos Mobarec, Piero Ricchiuto, Yupu Liang, William R. Mowrey, Parham Haddadi, Babak Ravandi, Naomi H. Philip, Tina Eliassi‐Rad, Mario Abdelmessih, Aparajita Chatterjee, Wei Ding

April 7, 2025article en

2 citations

Abstract

No abstract available for this paper.

BioinformaticsVol. 41(5)

AstraZeneca (United Kingdom) (GB), Northeastern University (US), Santa Fe Institute (US), Alliance Bioversity International - CIAT (IT), AstraZeneca (Brazil) (BR), AstraZeneca (United States) (US), Alexion Pharma (Switzerland) (CH)

AstraZeneca, Alexion Pharmaceuticals, Northwestern University

Openalex Percentile: Top 18%

Bioinformatics and Genomic Networks

1.61

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Topology-driven negative sampling enhances generalizability in protein–protein interaction prediction — Juan Carlos Mobarec, Piero Ricchiuto, et al. · Bioinformatics (2025) | TGRS Research Map | TGRS