Characterization of Enterobacter cloacae and Citrobacter freundii Species Complex Isolates with Decreased Susceptibility to Cephalosporins from United States Hospitals and Activity of Aztreonam–Avibactam and Comparator Agents (2019–2023)
Aztreonam-avibactam was highly active against cephalosporin-nonsusceptible ECLC and CFC, including MBL producers. The activities of ceftazidime-avibactam, meropenem-vaborbactam, and cefiderocol were compromised against CB-R isolates due to the high frequency of NDM producers.
Authors
- John H. Kimbrough (ORCID: https://orcid.org/0000-0002-0457-1543)
- Rodrigo E. Mendes (ORCID: https://orcid.org/0000-0002-8648-1137)
- Timothy B Doyle (ORCID: https://orcid.org/0000-0002-1083-8742)
- Hélio S. Sader (ORCID: https://orcid.org/0000-0001-7022-6644)
- Mariana Castanheira
Institutions
- JMI Laboratories (US)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-04-05
- DOI
- https://doi.org/10.3390/antibiotics14040382
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59