Antidepressant Non-refill as a Proxy Measure for Medication Acceptability in Electronic Health Records
Derived from structured data, antidepressant non-refill is a promising outcome measure for EHR-linked biobanks that partially reproduced antidepressant-CYP interactions. However, testing on larger datasets is necessary to understand whether it would be a useful for pharmacogenomic research.
Authors
- Suzette J. Bielinski (ORCID: https://orcid.org/0000-0002-2905-5430)
- Melissa Solares-Bravo (ORCID: https://orcid.org/0000-0003-1496-0013)
- Mark A. Frye (ORCID: https://orcid.org/0000-0001-6997-4215)
- Jorge A. Sánchez-Ruiz (ORCID: https://orcid.org/0000-0003-4282-7359)
- Joanna M. Biernacka (ORCID: https://orcid.org/0000-0001-9350-4440)
- Richard M. Weinshilboum (ORCID: https://orcid.org/0000-0002-4911-7985)
- Nicole I. Leibman (ORCID: https://orcid.org/0000-0002-4669-4576)
- Liewei Wang (ORCID: https://orcid.org/0000-0003-3818-8531)
- Gregory D. Jenkins (ORCID: https://orcid.org/0000-0001-6408-6227)
- Ayşegül Özerdem (ORCID: https://orcid.org/0000-0002-9455-5896)
- Nicolás A. Núñez (ORCID: https://orcid.org/0000-0003-0404-3529)
- Ahmed T. Ahmed (ORCID: https://orcid.org/0000-0003-4349-4509)
Institutions
- Mayo Clinic (US)
- University of South Carolina (US)
- Baylor College of Medicine (US)
- University of Utah (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Journal of Clinical Psychopharmacology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1097/jcp.0000000000002001
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00