Conversion of Mild Cognitive Impairment to Alzheimer’s Disease is Associated with Lateral Tract Degeneration of the Nucleus Basalis of Meynert (P10-3.019)
The aim of this work is to determine the changes in white matter integrity of the lateral and medial Nucleus Basalis of Meynert (NBM) tracts across time, between participants who either maintain a diagnosis of mild cognitive impairment (MCI) or develop Alzheimer’s disease (AD), to shed light on the differences that lead to progression to AD.
Authors
- Gang Seo
- Tatianna Howard
- A Negi (ORCID: https://orcid.org/0000-0002-4216-8317)
- Rachel A. Crockett (ORCID: https://orcid.org/0000-0001-8580-948X)
- Kevin B. Wilkins (ORCID: https://orcid.org/0000-0001-5907-4029)
- Helen M Bronte-Stewart (ORCID: https://orcid.org/0000-0002-1839-4541)
- Charlotte Casselton
- Annie K Abay
Institutions
- University of Oxford (GB)
- Stanford Medicine (US)
- Stanford University (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211486
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00