Evaluation of CHIT1 and SERPINA3 as Candidate Cerebrospinal Fluid Biomarkers of Progressive Biology in Multiple Sclerosis (S33.003)
To quantitatively confirm associations between chitotriosidase-1 (CHIT1) or serpin family A member 3 (SERPINA3) and measures of multiple sclerosis (MS) progressive biology and quantitatively assess ocrelizumab treatment effect on cerebrospinal fluid (CSF) levels of these biomarkers.
Authors
- Jenny Jiang (ORCID: https://orcid.org/0000-0003-0341-1385)
- Briana Cameron (ORCID: https://orcid.org/0000-0001-5940-8252)
- Akshaya Ramesh (ORCID: https://orcid.org/0000-0003-0205-0688)
- Jeffrey Marc Gelfand (ORCID: https://orcid.org/0000-0002-5121-3319)
- Xiaoming Jia (ORCID: https://orcid.org/0000-0002-5104-5431)
- Ryan C. Winger (ORCID: https://orcid.org/0000-0001-9160-6646)
- Christopher Harp (ORCID: https://orcid.org/0000-0001-7000-8743)
- Ann Herman
- Amit Bar-Or (ORCID: https://orcid.org/0000-0001-7179-0335)
- H.-Christian von Büdingen
- Anne Cross
- Chinaza Agbim
Institutions
- Roche (Switzerland) (CH)
- University of California, San Francisco (US)
- California University of Pennsylvania (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000210408
- Citations
- 1
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39