Comparative review of NETosis in Mouse and Human Models with a Focus on Subarachnoid Hemorrhage (P9-14.001)

Recent studies have found that neutrophil extracellular traps(NETs) are key players in the pathophysiology of subarachnoid hemorrhage, with research in both animal and human subjects elucidating the roles of NETs in exacerbating inflammation. We highlight the current knowledge and insights from animal models studying NETs in subarachnoid hemorrhage, alongside the current landscape in human research to map out the parallels and highlight the barriers between findings in both models, underscoring the need for translational research to bridge these gaps.