Neuropathy with Autoantibodies Against Septin Multimers in PNS Myelin Mimicking Lower Motor Neuron Disease (P4-11.028)
Severe neuropathies with predominant affection of motor fibers can mimic lower motor neuron disease (LMND) phenotypes such as in motor predominant chronic inflammatory demyelinating polyradiculoneuropathy and bulbar anti-IgLON5 disease. Given the fatal prognosis of LMND, identifying underlying autoimmune syndromes is crucial to provide treatment options to patients.
Authors
- Matthias Endres (ORCID: https://orcid.org/0000-0001-6520-3720)
- Helena Radbruch (ORCID: https://orcid.org/0000-0001-6941-3397)
- Stephanie Wernick
- Luise Appeltshauser (ORCID: https://orcid.org/0000-0001-5248-4009)
- Philipp Mertins (ORCID: https://orcid.org/0000-0002-2245-528X)
- Harald Prüß (ORCID: https://orcid.org/0000-0002-8283-7976)
- Divyanshu Dubey (ORCID: https://orcid.org/0000-0001-6865-9045)
- Marieluise Kirchner (ORCID: https://orcid.org/0000-0002-7049-534X)
- Friederike A. Arlt (ORCID: https://orcid.org/0000-0002-0112-8685)
- Hauke B. Werner (ORCID: https://orcid.org/0000-0002-7710-5738)
- Klemens Ruprecht (ORCID: https://orcid.org/0000-0003-1962-6014)
- Kathrin Borowski
- Andrew B. McKeon (ORCID: https://orcid.org/0000-0001-6856-8143)
- Lars Komorowski (ORCID: https://orcid.org/0000-0003-4698-3316)
- Ramona Miske (ORCID: https://orcid.org/0000-0002-9424-4676)
- Kathrin Doppler (ORCID: https://orcid.org/0000-0003-2883-0009)
- Andreas Meisel (ORCID: https://orcid.org/0000-0001-7233-5342)
- Werner Stenzel (ORCID: https://orcid.org/0000-0002-1143-2103)
- Elisa Sánchez-Sendin (ORCID: https://orcid.org/0000-0002-0939-8911)
- Madeleine Scharf
- Sophie Huemmert
Institutions
- Max Delbrück Center (DE)
- German Center for Neurodegenerative Diseases (DE)
- WinnMed (US)
- Humboldt-Universität zu Berlin (DE)
- Euroimmun Medizinische Labordiagnostika (Germany) (DE)
- Universitätsklinikum Würzburg (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Max Planck Institute for Multidisciplinary Sciences (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211012
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00