Integrated Genomic, Proteomic, and Transcriptomic Profiling Support Cathepsin-B as a Drug Repurposing Target in Cerebral Small Vessel Disease (S2.001)
Integrate genomic, proteomic, and transcriptomic data to identify proteins that may target and slow the progression of White Matter Hyperintensities (WMH).
Authors
- Shufan Huo
- Lauren Hachmann Sansing (ORCID: https://orcid.org/0000-0002-6898-1680)
- Cyprien A. Rivier (ORCID: https://orcid.org/0000-0002-1148-1829)
- Guido J. Falcone (ORCID: https://orcid.org/0000-0002-6407-0302)
- Xianjun Dong (ORCID: https://orcid.org/0000-0002-8052-9320)
- Kevin Navin Sheth (ORCID: https://orcid.org/0000-0003-2003-5473)
- Seyedmehdi Payabvash (ORCID: https://orcid.org/0000-0003-4628-0370)
- Daniela Renedo (ORCID: https://orcid.org/0000-0003-4120-6649)
- Richa Sharma (ORCID: https://orcid.org/0000-0003-0798-2353)
- Santiago Clocchiatti‐Tuozzo (ORCID: https://orcid.org/0000-0001-5377-434X)
- Srikant Rangaraju
Institutions
- Emory University (US)
- Yale University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211788
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00