Novel Serum Biomarker Associations with 7 Tesla MRI-defined Cortical Lesions, Leptomeningeal Enhancement, and Deep Gray Matter Volume in Early Multiple Sclerosis (P9-1.017)
Because of the persisting unmet need to identify biomarkers with prognostic clinical utility in MS, the objective of the present study is to characterize the relationship between 7 Tesla MRI-defined measures of disease severity (gray matter demyelinating lesions, brain atrophy, and meningeal inflammation) and serological immune alterations in patients with early MS.
Authors
- Renxin Chu (ORCID: https://orcid.org/0000-0002-1668-238X)
- Shrishti Saxena (ORCID: https://orcid.org/0000-0003-3429-5671)
- Brian C. Healy (ORCID: https://orcid.org/0000-0001-5272-2425)
- Tanuja Chitnis (ORCID: https://orcid.org/0000-0002-9897-4422)
- Rohit Bakshi (ORCID: https://orcid.org/0000-0001-8601-5534)
- Andrei Miclea (ORCID: https://orcid.org/0000-0001-9056-1298)
- Howard L. Weiner (ORCID: https://orcid.org/0000-0003-0203-9681)
- Jonathan Zurawski (ORCID: https://orcid.org/0000-0002-2896-8369)
- Molly Quattrucci
- Hrishikesh Lokhande (ORCID: https://orcid.org/0000-0002-8257-1901)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000210386
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00