Differential Reductions of in vivo Activity in CA1 Pyramidal Neuron Subpopulations during Spatial Working Memory in the 5xFAD Model of Amyloidosis (P5-3.008)

We compared markers of neuronal activity elicited during spatial working memory in the 5xFAD amyloidosis model versus WT mice across subpopulations of dorsal hippocampal CA1 defined by neuronal location along the radial (superficial, deep) and transverse (CA1a, CA1c) axes.

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000210339
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Differential Reductions of in vivo Activity in CA1 Pyramidal Neuron Subpopulations during Spatial Working Memory in the 5xFAD Model of Amyloidosis (P5-3.008)

Arjun V. Masurkar, Dylan Rhodes, Thangavel Mohankumar, Isabel Reyes et al.
Neurology
Alzheimer's disease research and treatments
article

Differential Reductions of in vivo Activity in CA1 Pyramidal Neuron Subpopulations during Spatial Working Memory in the 5xFAD Model of Amyloidosis (P5-3.008)

Arjun V. Masurkar, Dylan Rhodes, Thangavel Mohankumar, Isabel Reyes, Chengju Tian
article en

Abstract

We compared markers of neuronal activity elicited during spatial working memory in the 5xFAD amyloidosis model versus WT mice across subpopulations of dorsal hippocampal CA1 defined by neuronal location along the radial (superficial, deep) and transverse (CA1a, CA1c) axes.

NeurologyVol. 104(7_Supplement_1)
New York University (US)
Openalex Percentile: Top 91%
Alzheimer's disease research and treatments
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