The Orexin 2 Receptor Agonist ALKS 2680 in Patients with Narcolepsy Type 1: An Initial Proof of Concept Phase 1b Study (P8-4.004)

To present the results from a randomized, double-blind, phase 1b study assessing the safety, tolerability, and pharmacodynamics of ALKS 2680 in patients with narcolepsy type 1 (NT1).

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000210498
Citations
2
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
2.86
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article

The Orexin 2 Receptor Agonist ALKS 2680 in Patients with Narcolepsy Type 1: An Initial Proof of Concept Phase 1b Study (P8-4.004)

Brendon J. Yee, Daniel J. Smith, Ronald R. Grunstein, Julia L. Chapman et al.
2 citations
Neurology
Sleep and Wakefulness Research
2.86
article

The Orexin 2 Receptor Agonist ALKS 2680 in Patients with Narcolepsy Type 1: An Initial Proof of Concept Phase 1b Study (P8-4.004)

Brendon J. Yee, Daniel J. Smith, Ronald R. Grunstein, Julia L. Chapman, Jandira Ramos, Bhaskar Rege, A D’Rozario, Craig Hopkinson, Sergey Yagoda
article en
2 citations

Abstract

To present the results from a randomized, double-blind, phase 1b study assessing the safety, tolerability, and pharmacodynamics of ALKS 2680 in patients with narcolepsy type 1 (NT1).

NeurologyVol. 104(7_Supplement_1)
Alkermes (Ireland) (IE), Woolcock Institute of Medical Research (AU)
Good health and well-being
Openalex Percentile: Top 11%
Sleep and Wakefulness Research
2.86
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