APOE e4 Linked Effects on Neuropathology and Clinical Features in Dementia with Lewy Bodies (S1.009)
We aimed to assess APOE e4-associated effects on α-synuclein pathology and Alzheimer’s co-pathology in dementia with Lewy bodies (DLB), and to explore the impact of APOE e4 on DLB-specific clinical features, including fluctuating cognition, visual hallucinations, rapid eye movement sleep behavior disorder (RBD) and parkinsonism.
Authors
- Stephen N. Gomperts (ORCID: https://orcid.org/0000-0002-0083-0077)
- Anna E. Goodheart
- Erin Peterec
- Rong Ye (ORCID: https://orcid.org/0000-0003-3855-567X)
Institutions
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211816
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00