Safety and Effectiveness of Fenfluramine for the Treatment of Seizures in Lennox-Gastaut Syndrome: Results From the Final Analysis of an Open-Label Extension Study (P8-9.002)

To describe the final long-term safety and effectiveness data from a fenfluramine (FFA) open-label extension (OLE) study in participants with Lennox-Gastaut syndrome (LGS) (NCT03355209).

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000210533
Primary Topic
Epilepsy research and treatment
Type
article
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article

Safety and Effectiveness of Fenfluramine for the Treatment of Seizures in Lennox-Gastaut Syndrome: Results From the Final Analysis of an Open-Label Extension Study (P8-9.002)

Rima Nabbout, David Dai, Renzo Guerrini, Diego Morita et al.
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Neurology
Epilepsy research and treatment
article

Safety and Effectiveness of Fenfluramine for the Treatment of Seizures in Lennox-Gastaut Syndrome: Results From the Final Analysis of an Open-Label Extension Study (P8-9.002)

Rima Nabbout, David Dai, Renzo Guerrini, Diego Morita, António Gil‐Nagel, Kelly G. Knupp, Berten Ceulemans, Katherine C. Nickels, Ingrid Eileen Scheffer, Sameer M. Zuberi, Mélanie Langlois, Michael Lock, Timothy Minh, Kate Riney, Amélie Lothe, Joseph Sullivan, Rebecca Zhang-Roper, Ronald L. Davis, Lieven Lagae
article en

Abstract

To describe the final long-term safety and effectiveness data from a fenfluramine (FFA) open-label extension (OLE) study in participants with Lennox-Gastaut syndrome (LGS) (NCT03355209).

NeurologyVol. 104(7_Supplement_1)
Royal Children's Hospital (AU), The University of Queensland (AU), University of California, San Francisco (US), Université Paris Cité (FR), Royal Hospital for Children (GB), WinnMed (US), Children's Hospital Colorado (US), Antwerp University Hospital (BE), Syneos Health (United States) (US), UCSF Benioff Children's Hospital (US), ERN GUARD-Heart (NL), Murdoch Children's Research Institute (AU), Hospital Ruber Internacional (ES), Children's Health Queensland Hospital and Health Service (AU), University of Florence (IT), University of Colorado Denver (US), KU Leuven (BE)
Good health and well-being
Openalex Percentile: Top 91%
Epilepsy research and treatment
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