Prevalence of FGF14-mediated Spinocerebellar Ataxia 27B (SCA27B) in a United States Cohort (P6-5.015)
Repeat expansions in the FGF14 gene cause spinocerebellar ataxia 27B (SCA27B), a slowly progressive adult-onset cerebellar ataxia. This may be a common genetic cause of adult-onset ataxia, with cohort studies suggesting diagnostic rates of between 10–61% in various populations worldwide, however, prevalence studies have yet to be performed in the United States.
Authors
- Brent L. Fogel (ORCID: https://orcid.org/0000-0001-9831-1576)
- Sonya Watson (ORCID: https://orcid.org/0009-0002-1461-6829)
- Anirudh N. Eranki (ORCID: https://orcid.org/0000-0002-4856-9787)
- Hannah Stevens (ORCID: https://orcid.org/0000-0003-3394-9768)
- Darice Y. Wong
- Veronica S. Avila
Institutions
- UCLA Health (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000210524
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00