The Associations of CSF ApoE and C1q With Alzheimer’s Disease Biomarkers (P3-3.011)
The involvement of Complement 1q(C1q) and Apolipoprotein E (ApoE) in the progression of Alzheimer’s disease (AD) is complex due to the previously reported association between neuroinflammation and AD pathology. To investigate the role of C1q and ApoE interaction in neuroinflammation and AD pathology, we examined the correlation between cerebrospinal fluid (CSF) C1q, CSF ApoE, and CSF neuroinflammatory biomarkers and AD core biomarkers.
Authors
- Zuo-Teng Wang (ORCID: https://orcid.org/0000-0002-7404-1759)
- Lan Tan (ORCID: https://orcid.org/0000-0002-8759-7588)
- Yujing Lin
Institutions
- Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211094
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00