Food Effect Study of Fosigotifator, an eIF2B Activator being developed as a Potential Treatment for Amyotrophic Lateral Sclerosis, Vanishing White Matter Disease, and Major Depressive Disorder (P8-2.011)
To assess the pharmacokinetics following administration of a single oral dose of fosigotifator granules in the fed state compared to fasted state and assess the acceptability of administration with soft foods
Authors
- Mallika Gopalkrishnan
- Shaofei Zhao (ORCID: https://orcid.org/0009-0005-7927-8113)
- Nidhi Prem
- Matthew Rosebraugh (ORCID: https://orcid.org/0000-0002-8333-7738)
- Yi Rang Han (ORCID: https://orcid.org/0009-0004-1894-9019)
- Bill Cho
- Anna Jeong
- Raaidah Saari-Nordhaus
Institutions
- AbbVie (United States) (US)
- San Diego State University, Imperial Valley Campus (US)
- AbbVie (Japan)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000210633
- Citations
- 1
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81