Large-Scale Whole-Exome Sequencing Analyses Identified Protein-Coding Variants Associated with Immune-Mediated Diseases in 350,770 Adults (S38.005)
Our objectives are: (1) identify putative variants across 40 autoimmune diseases, including Guillain-Barre syndrome, myasthenia gravis, multiple sclerosis, narcolepsy, at an exome-wide level; (2) elucidate clinical impacts, and underlying biological pathways of these variants and to identify potential therapeutic targets.
Authors
- Jin‐Tai Yu (ORCID: https://orcid.org/0000-0002-7686-0547)
- Liu Yang (ORCID: https://orcid.org/0000-0001-9408-6797)
Institutions
- Fudan University (CN)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211194
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00