Severe Necrotizing Myositis in a Patient with Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR), Melanoma Differentiation-Associated Gene 5 (MDA-5), Clinically Amyopathic Dermatomyositis 140 (CADM-140), Nuclear Matrix Protein 2 (NXP-2), an
To present a case of severe immune mediated necrotizing myositis in a patient with autoantibodies to HGMCR, MDA-5, CADM-140, NXP-2, and RNP without dermatologic involvement that was minimally responsive to intravenous immune globulin (IVIG) requiring cyclophosphamide.
Authors
- Kyle N. Kaneko (ORCID: https://orcid.org/0009-0001-2416-0688)
- Erik Ortega
- Kevin Dang (ORCID: https://orcid.org/0000-0001-5695-926X)
Institutions
- Barrow Neurological Institute (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000208370
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00