The Continued Need of Pediatric Management Guidelines for Pediatric Stroke with Associated Patent Foramen Ovale: A Case Series (P5-6.007)

Patent foramen ovale (PFO) is a congenital cardiac anomaly resulting from the incomplete closure of the atrial septum, allowing blood to shunt from the right to the left atrium and bypass pulmonary filtration. This shunting can lead to paradoxical embolism, where emboli enter systemic circulation and potentially cause brain ischemia. Due to this possibility, PFO’s have been increasingly recognized as potential contributors to cryptogenic stroke. This paper examines four pediatric cases of cryptogenic strokes associated with PFOs and highlights the current lack of specific guidelines for PFO closure in the pediatric population.

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000208467
Citations
1
Primary Topic
Cardiovascular and Diving-Related Complications
Type
article
Field-Weighted Citation Impact
1.52
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article

The Continued Need of Pediatric Management Guidelines for Pediatric Stroke with Associated Patent Foramen Ovale: A Case Series (P5-6.007)

Loren McLendon, Harry S. Abram, Sam Kamoroff, Rachna Karumuri
1 citations
Neurology
Cardiovascular and Diving-Related Complications
1.52
article

The Continued Need of Pediatric Management Guidelines for Pediatric Stroke with Associated Patent Foramen Ovale: A Case Series (P5-6.007)

Loren McLendon, Harry S. Abram, Sam Kamoroff, Rachna Karumuri
article en
1 citations

Abstract

Patent foramen ovale (PFO) is a congenital cardiac anomaly resulting from the incomplete closure of the atrial septum, allowing blood to shunt from the right to the left atrium and bypass pulmonary filtration. This shunting can lead to paradoxical embolism, where emboli enter systemic circulation and potentially cause brain ischemia. Due to this possibility, PFO’s have been increasingly recognized as potential contributors to cryptogenic stroke. This paper examines four pediatric cases of cryptogenic strokes associated with PFOs and highlights the current lack of specific guidelines for PFO closure in the pediatric population.

NeurologyVol. 104(7_Supplement_1)
University of Florida (US), Jacksonville University (US), Nemours Children's Health System (US)
Good health and well-being
Openalex Percentile: Top 20%
Cardiovascular and Diving-Related Complications
1.52
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The Continued Need of Pediatric Management Guidelines for Pediatric Stroke with Associated Patent Foramen Ovale: A Case Series (P5-6.007) — Loren McLendon, Harry S. Abram, et al. · Neurology (2025) | TGRS Research Map | TGRS