Blood-Based Inflammatory Protein Biomarker Panel for the Prediction of Relapse and Severity in Patients with Neuromyelitis Optica Spectrum Disorder: A Prospective Cohort Study (P11-8.015)

In this study, we aimed to use the proximity extension assay (PEA) in a prospective cohort to identify novel potential biomarkers and assess their predictive power. Moreover, we created two prognostic models by using a biomarker panel to increase prognostic accuracy and confirm the effectiveness of the model in a separate validation cohort. Thus, we obtained a more comprehensive overview of the acute-phase plasma proteins of NMOSD and developed a more precise plasma biomarker prediction model to reflect the immunological characteristics of NMOSD.