Carisbamate Treatment of Adult and Pediatric Patients With Lennox-Gastaut Syndrome: A Phase I Pharmacokinetic Dose-Escalation Study (P9-9.007)

Assess, in a phase 1, open-label study, pharmacokinetics (PK), safety, and tolerability of single-dose (SD) and multiple-dose (MD) adjunctive carisbamate in patients ≥2 years old with Lennox-Gastaut syndrome (LGS).

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000208551
Citations
2
Primary Topic
Ion Transport and Channel Regulation
Type
article
Field-Weighted Citation Impact
1.61
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article

Carisbamate Treatment of Adult and Pediatric Patients With Lennox-Gastaut Syndrome: A Phase I Pharmacokinetic Dose-Escalation Study (P9-9.007)

David G. Vossler, Vijay Vashi
2 citations
Neurology
Ion Transport and Channel Regulation
1.61
article

Carisbamate Treatment of Adult and Pediatric Patients With Lennox-Gastaut Syndrome: A Phase I Pharmacokinetic Dose-Escalation Study (P9-9.007)

David G. Vossler, Vijay Vashi
article en
2 citations

Abstract

Assess, in a phase 1, open-label study, pharmacokinetics (PK), safety, and tolerability of single-dose (SD) and multiple-dose (MD) adjunctive carisbamate in patients ≥2 years old with Lennox-Gastaut syndrome (LGS).

NeurologyVol. 104(7_Supplement_1)
University of Washington (US), SK Life Science (United States) (US)
Good health and well-being
Openalex Percentile: Top 18%
Ion Transport and Channel Regulation
1.61
DOISourceOpenAlex
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Carisbamate Treatment of Adult and Pediatric Patients With Lennox-Gastaut Syndrome: A Phase I Pharmacokinetic Dose-Escalation Study (P9-9.007) — David G. Vossler, Vijay Vashi · Neurology (2025) | TGRS Research Map | TGRS